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Do ‘Natural GLP-1 Supplements’ Actually Work As Well As O...

Here’s what the experts fr think about the trend. At this point it’s no secret that GLP-1s can be an effective strategy for losing weight.

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Tuesday, December 23, 2025 📖 2 min read
Do ‘Natural GLP-1 Supplements’ Actually Work As Well As O...
Image: Womens Health

What’s Happening

Listen up: Here’s what the experts fr think about the trend.

At this point it’s no secret that GLP-1s can be an effective strategy for losing weight. They’re not always that easy to get your hands on—and if they are, they might not come with the most pleasant side effects . (shocking, we know)

(In fact, between 50 and 75 percent of people stop taking them within a year, per a 2024 study in JAMA Network Open .

The Details

) Enter: “ natural GLP-1 supplements . ” Yup, supplements that promise to give similar results to those mighty weight loss meds without the same hassle.

Between berberine and psyllium husk duking it out for the title of “nature’s Ozempic” and all the new concoctions being developed by brands, there’s no shortage of options on the market. Kourtney Kardashian’s Lemme brand has Lemme GLP-1 Daily, touted on Instagram as “a breakthrough innovation in metabolic health, formulated to naturally boost your body’s GLP-1 production, reduce appetite, and promote healthy weight loss.

Why This Matters

” Supergut sells a GLP-1 Daily Support , while Pendulum offers a GLP-1 Probiotic . “This multi-strain probiotic is formulated with beneficial bacteria that naturally increase GLP-1, the ‘un-hunger’ hormone that helps curb cravings and appetite,” according to the Pendulum site . Many of these supplements are specifically marketed to women, playing on the idea that out-of-whack hormones might be contributing to weight gain.

This is the kind of health news that affects everyday decisions.

Key Takeaways

  • Obviously, there’s one critical question: do these supplements actually work?
  • We tapped obesity medicine physicians for their answer.
  • Meet the the experts: Kunal Shah , MD, is an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center.
  • Mir Ali , MD, is a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center.

The Bottom Line

Mir Ali , MD, is a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center. What is a natural GLP-1 supplement?

Sound off in the comments.

Originally reported by Womens Health

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