Resident Evil Requiem’s endings, broke down

What’s Happening

Okay so Resident Evil Requiem ends Claire and Leon’s adventure with an avalanche of lore.

Here’s everything you need to make sense of it all. Follow Followed Like Thread Link copied to clipboard Add us on By Giovanni Colantonio Published Mar 1, 2026, 6:00 PM EST Explainer Theres a whole lot of lore to sort through Related How long does it take to beat Resident Evil Requiem Resident Evil Requiem walkthrough part 6: The Basement Resident Evil Requiem walkthrough part 5: Garage, Isolation Ward, and the Attic in the Chronic Care Center Resident Evil Requiem’s endings, broke down Image: Capcom Sign in to your Polygon account Resident Evil Requiem has a complicated story, though that shouldn’t come as a surprise to anyone who has kept up with the series over 30 years. (shocking, we know)

Capcom’s survival horror games are filled with evil organizations and similarly-named viruses that can be tough to keep straight.

The Details

At first, Requiem seems to be getting away from all that with its new character, Grace Ashcroft, but it soon becomes clear that’s not the case. In fact, Requiem might be the most lore-intensive game in Resident Evil’s history, thanks to how many loose threads it attempts to tie up in its ending.

Even if you’ve played every game in the series, the finale might still leave you scratching your head with its mess of proper nouns. To help you unpack it all, here’s a breakdown of exactly what happens at the end of Resident Evil Requiem and how it ties into the series’ past.

Why This Matters

This article contains spoilers for Resident Evil Requiem . A little setup is required, because there are a few mysteries swirling around Requiem ahead of its ending. Kennedy is investigating what’s been dubbed Raccoon City Syndrome.

This is the kind of news that gets gamers talking across social media.

Key Takeaways

Those who survived the bombing of Raccoon City back in 1998’s Resident Evil 3: Nemesis are suffering long-term side effects.
They have developed black rashes on their skin and are slowly dying from the infection.
Leon has a case of it himself, so he’s particularly invested in figuring out what has happened.
Meanwhile, Grace Ashcroft is kidnapped by Dr.